In comparison to IgM antibodies, IgG antibodies have a relatively high affinity and persist in the circulation for a really long time. The IgG antibodies express their predominant activity during a secondary antibody response. The IgG accounts for about 75 percent of serum antibodies in humans. The immunoglobulin G (IgG) is the most common antibody found in the blood and a major effector molecule of the humoral response. They are two common types of antibodies found in the blood. So, IgG and IgM represent different stages of an immune response. A serology test, however, does not detect the presence of the virus, but rather detect the antibodies that are produced by our body is fighting the virus. An antibody test (serology test) is therefore very useful in diagnosing an acute infection. For example, the antibody for SARS-CoV-2 is not the same as the antibody for any other virus, such as the chickenpox or HIV. They protect our body against antigens such as viruses, toxins or bacteria.Ī serology test can be used to detect the antibodies in our system because our body builds different antibodies to fight off different antigens. Also known as immunoglobulins, antibodies are produced by our immune system as part of an immune response.
So, antibodies are nothing but large protein molecules that fight off against foreign objects that try to enter our body. The antibodies attack the virus and eliminate the virus from the system. When an individual is infected with a virus, like the SARS-Cov-2 which causes COVID-19, the person’s body starts to develop an immune response naturally by building antibodies to the virus.
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